Acute variation of biochemical markers of muscle damage following a 21‐km, half‐marathon run
Why the study?
Does a 21-km half-marathon run increase biochemical markers of muscle and cardiac damage in healthy trained males?
Population
15 healthy, trained, Caucasian males
Design
Cohort
Follow-up
24 hours
Authors
Discussion
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Member takes
Implication
Supports no myocardial injury after half-marathon in trained males; leaves open generalizability to other distances or populations.
Structured PICO
Does a 21-km half-marathon run increase biochemical markers of muscle and cardiac damage in healthy trained males?
P
Population
15 healthy, trained, Caucasian males
I
Intervention
21-km half-marathon run (sub-maximal exercise)
O
Outcome
Biochemical markers of muscle and cardiac damage (troponin T, AST, CK, CK MB, LDH, and myoglobin) measured immediately after, 3 h, 6 h, and 24 h post-runsurrogate
Sub-maximal exercise such as a 21-km half-marathon run significantly increases biomarkers of skeletal muscle damage for up to 24 hours without causing biochemical signs of myocardial damage.
Cite This Study
Lippi et al. (2008) studied this question.