Clear Cell Melanoblastoma

In a 37-year-old male, a melanoblastoma was observed consisting for the most part of clear vacuolated cells. The tumour cells in the lymph node metastasis were of common appearance typical for melanoblastomas of the alveolar type. The presence of clear cells can be misleading in the establishment of the accurate bioptic diagnosis. The behaviour of the clear cell melanoblastoma shows no difference from other types of this tumour. No definitive explanation of clear cell transformation in melanoblastomas is given at present.