Why the study?
Does fetal echocardiography at 11 to 14 weeks' gestation reliably detect congenital heart disease compared to second-trimester echocardiography in fetuses?
Population
870 fetuses who underwent fetal echocardiography at 11 to 14 and 18 to 22 weeks' gestation from 2005 to 2010
Comparison
Fetal echocardiography at 11 to 14 weeks'… vs Fetal echocardiography at 18 to 22 weeks'…
Design
Cohort
Authors
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Early fetal echocardiography warrants caution due to discordances; leaves open optimal timing and protocols for congenital heart disease screening.
Does fetal echocardiography at 11 to 14 weeks' gestation reliably detect congenital heart disease compared to second-trimester echocardiography in fetuses?
First-trimester fetal echocardiography allows early detection of major congenital heart disease, though some defects may be missed or develop later in gestation.
Volpe et al. (2012) studied this question.
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