What question did this study set out to answer?

To determine whether the magnitude of post-exercise muscle glycogen depletion regulates the subsequent rate of glycogen resynthesis during carbohydrate feeding.

January 1, 1991Medicine & Science in Sports & Exercise

Influence of muscle glycogen depletion on the rate of resynthesis

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Authors

JZJ ZachwiejaPoznan University of Medical Sciences DCD. L. CostillBall State University DPDavid D. PascoeGlaxoSmithKline (Netherlands)

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Implication

Experimental study demonstrates faster muscle glycogen resynthesis following greater depletion in male cyclists, suggesting glycogen deficit accelerates early post-exercise recovery.

Key Points

To determine whether the magnitude of post-exercise muscle glycogen depletion regulates the subsequent rate of glycogen resynthesis during carbohydrate feeding.
Six male cyclists performed an exercise protocol creating high depletion in one leg (single-leg cycling, sprints, and bilateral cycling) and low depletion in the contralateral leg (bilateral cycling only).
Participants rested for 6 hours post-exercise and consumed a 24% carbohydrate solution every 20 minutes (total intake 0.7 g·kg⁻¹·h⁻¹).
Vastus lateralis muscle biopsies were obtained immediately post-exercise and at 2 and 6 hours of recovery to assess glycogen concentration and glycogen synthase activity.
Immediate post-exercise glycogen reduction was significantly greater in the high-depletion leg (93.9 ± 11.6 mmol·kg⁻¹ w.w.) than in the low-depletion leg (49.3 ± 5.7 mmol·kg⁻¹ w.w., P < 0.01).
The rate of muscle glycogen resynthesis across 6 hours was significantly higher in the high-depletion leg compared to the low-depletion leg (8.8 ± 2.4 vs 3.0 ± 1.0 mmol·kg⁻¹·h⁻¹ w.w., P < 0.05).
Glycogen synthase activity ratio (I/D) was significantly higher in the high-depletion leg immediately post-exercise (0.45 ± 0.05 vs 0.24 ± 0.04, P < 0.01) and at 2 hours of recovery (0.54 ± 0.06 vs 0.27 ± 0.06, P < 0.01), before normalizing by 6 hours.

Cite This Study

Zachwieja et al. (1991) studied this question.

synapsesocial.com/papers/6a717f9cf44fa9f079df49aa https://doi.org/10.1249/00005768-199101000-00008

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Implication

Experimental study demonstrates faster muscle glycogen resynthesis following greater depletion in male cyclists, suggesting glycogen deficit accelerates early post-exercise recovery.

Influence of muscle glycogen depletion on the rate of resynthesis

Discussion

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Implication

Key Points

Cite This Study

Influence of muscle glycogen depletion on the rate of resynthesis

Discussion

Member takes

Implication

Key Points

Cite This Study

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