August 15, 2025Frontiers in PhysiologyOpen Access

Exercise- and diet-induced glycogen depletion impairs performance during one-legged constant-load, high-intensity exercise in humans

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Authors

MTMartin ThomassenUniversity of Copenhagen MMMichael J. McKennaHealth and Safety Executive HOHugo OlmedillasUniversidad de Oviedo

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Implication

Exercise-induced glycogen depletion reduces performance during one-legged exercise, suggesting significant implications for muscle function and contractility.

Key Points

Glycogen depletion reduced time to task failure by 40% during one-legged exercise, impairing performance.
MVC and twitch force were unaffected at rest, yet contractile characteristics worsened after exercise to task failure.
Assessment involved one-legged and two-legged exercises, incorporating various muscular performance measurements.
Glycogen's role in high-intensity exercise highlights the need for optimized diet and training strategies.

Cite This Study

Thomassen et al. (2025) studied this question.

synapsesocial.com/papers/68af50a1ad7bf08b1ead8a9d https://doi.org/10.3389/fphys.2025.1564523

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Implication

Exercise-induced glycogen depletion reduces performance during one-legged exercise, suggesting significant implications for muscle function and contractility.

Exercise- and diet-induced glycogen depletion impairs performance during one-legged constant-load, high-intensity exercise in humans

Discussion

Member takes

Implication

Key Points

Cite This Study

Exercise- and diet-induced glycogen depletion impairs performance during one-legged constant-load, high-intensity exercise in humans

Discussion

Member takes

Implication

Key Points

Cite This Study

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