Arterial Oxygen Saturation in Cirrhosis of the Liver

Article1 November 1940ARTERIAL OXYGEN SATURATION IN CIRRHOSIS OF THE LIVERROBERT C. DARLING, M.D.ROBERT C. DARLING, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-14-5-898 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe finding of a severe degree of oxygen unsaturation in the arterial blood of patients with cirrhosis of the liver has been reported by Snell.1 Later, Keyes and Snell2 studied a further series with oxygen dissociation curves, and found a small but significant shift in the curve from the accepted normal value. In this second series the oxygen unsaturation of the arterial blood was less marked than in the first series. From this work it was concluded that the hemoglobin in liver disease had properties somewhat different from normal.Since there are few objective tests for measuring the disturbances of...Bibliography1. SNELL AM: The effects of chronic disease of the liver on the composition and physicochemical properties of blood: changes in the serum proteins; reduction in the oxygen saturation of the arterial blood, ANN. INT. MED., 1935, ix, 690-711. Google Scholar2. KEYESSNELL AAM: Respiratory properties of the arterial blood in normal man and in patients with disease of the liver: position of the oxygen dissociation curve, Jr. Clin. Invest., 1938, xvii, 59-67. CrossrefGoogle Scholar3. DILLGRAYBIELHURTADOTAQUINI DBAAAC: Der Gasaustausch in den Lungen in Alter, Ztschr. f. Altersforsch., 1940, ii, 20-33. Google Scholar4. DILLEDWARDSCONSOLAZIO DBHTWV: Blood as a physicochemical system. XI. Man at rest, Jr. Biol. Chem., 1937, cxviii, 635-648. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, N. Y.*Received for publication July 3, 1940.Research Service (Formerly Research Division for Chronic Diseases), First Division, Welfare Hospital, Department of Hospitals, New York City, and Department of Medicine, College of Physicians and Surgeons, Columbia University, New York City. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThe oxyhemoglobin dissociation curve in health and diseaseClosing volume — A test of small airway function?Hypertrophic osteoarthropathy with arthritis and synovial calcification in a patient with alcoholic cirrhosisCirrhosis, cyanosis and polycythaemia: Multiple pulmonary arteriovenous anastomosesOxyhemoglobin Dissociation in Patients with Hepatic EncephalopathyArterial Changes in the Lungs in Cirrhosis of the Liver — Lung Spider NeviSystemic Circulatory Adjustments in Hepatic DiseaseVENOARTERIAL SHUNTS IN CIRRHOSIS OF THE LIVER 1 November 1940Volume 14, Issue 5Page: 898-902KeywordsBloodCirrhosisHemoglobinHospital medicineLiverLiver diseasesOxygenSurgeons Issue Published: 1 November 1940 PDF downloadLoading ...