What question did this study set out to answer?

To evaluate the clinical, etiologic, and epidemiologic characteristics of acute lower respiratory tract infections (ALRI) in children younger than five years of age.

November 1, 1990Clinical Infectious Diseases

Etiologic and Clinical Evaluation of Acute Lower RespiratoryThact Infections in Young Argentinian Children: An Overview

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Authors

MWMercedes WeissenbacberUniversity of Buenos Aires GCGuadalupe CarballalConsejo Nacional de Investigaciones Científicas y Técnicas MÁMaría Mercedes ÁvilaUniversity of Vermont

Discussion

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Implication

Observational study reveals primary viral and bacterial pathogens in young children with lower respiratory infections, highlighting respiratory syncytial virus and pneumococcus burdens.

Key Points

To evaluate the clinical, etiologic, and epidemiologic characteristics of acute lower respiratory tract infections (ALRI) in children younger than five years of age.
Assessed 1,003 children under 5 years of age (805 inpatients and 198 outpatients) presenting with ALRI over a 40-month period in Argentina.
Collected nasopharyngeal aspirates, blood, urine, and throat swabs upon initial clinical presentation.
Identified viruses via indirect immunofluorescence and cell culture; detected bacteria via blood/pleural fluid cultures, immunofluorescence, and complement-fixation testing.
Respiratory syncytial virus was the most frequently isolated viral agent, followed by adenovirus, parainfluenza virus, and influenza virus.
Streptococcus pneumoniae was the most prevalent bacterial isolate, followed by Bordetella pertussis and Haemophilus influenzae type b.
The overall patient fatality rate was 3.8% among hospitalized children diagnosed with pneumonia or bronchiolitis.

Cite This Study

Weissenbacber et al. (1990) studied this question.

synapsesocial.com/papers/6a7182d88031ec7bb1dd00be https://doi.org/10.1093/clinids/12.supplement_8.s889

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Implication

Observational study reveals primary viral and bacterial pathogens in young children with lower respiratory infections, highlighting respiratory syncytial virus and pneumococcus burdens.