Why the study?
Noninvasive alternatives to biopsy for assessing interstitial fibrosis and tubular atrophy (IFTA), the major determinant of kidney transplant failure, remain profoundly limited.
Do ultrasound and MR elastography detect early interstitial fibrosis and tubular atrophy in pediatric kidney allografts?
Comparison
Ultrasound elastography and MR elastography in transplant recipients vs healthy controls
Design
Pilot study
Authors
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Elastography may aid noninvasive IFTA detection in pediatric transplants; leaves open clinical utility pending validation studies.
Do ultrasound and MR elastography detect early interstitial fibrosis and tubular atrophy in pediatric kidney allografts?
Ultrasound and MR elastography show potential as noninvasive tools for detecting low-grade interstitial fibrosis and tubular atrophy in pediatric kidney allografts.
Elsingergy et al. (2023) studied this question.
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