Why the study?
Does an antihypertensive regimen based on low dose diuretic therapy reduce the incidence of fatal and nonfatal stroke in elderly patients with isolated systolic hypertension?
Does an antihypertensive regimen based on low dose diuretic therapy reduce the incidence of fatal and nonfatal stroke in elderly patients with isolated systolic hypertension?
A low-dose diuretic regimen significantly reduces the risk of stroke, coronary heart disease, and major cardiovascular events in elderly patients with isolated systolic hypertension.
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Supports low-dose diuretics in elderly ISH; confirms SHEP while leaving contemporary relevance open.
Moyé et al. (1993) studied this question.
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