What question did this study set out to answer?

To investigate the levels of serum enzymes, particularly CK-MB, post-coronary bypass surgery and their correlation with surgical characteristics.

January 1, 1979Scandinavian Journal of Thoracic and Cardiovascular Surgery

Serum Enzymes with Special Reference to CK-MB Following Coronary Bypass Surgery

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Population

25 patients undergoing coronary bypass operations

Design

Case_series

Follow-up

At least 4 days postoperatively

Authors

SSStellan StrömS:t Eriks Ögonsjukhus RBRutger BendzSt Göran's Children's Hospital COChristian OlinLinköping University

Discussion

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Implication

CK-MB elevation may reflect ECC/AC duration rather than injury post-CABG; case report leaves open optimal enzyme for myocardial assessment.

Key Points

To investigate the levels of serum enzymes, particularly CK-MB, post-coronary bypass surgery and their correlation with surgical characteristics.
Analyzed serum levels of total CK, CK-MB, ASAT, ALAT, and LD-T in 25 patients following coronary bypass surgery.
Monitored peak activity levels of CK and their correlation with electrocardiographic findings and surgical parameters, such as duration of extracorporeal circulation and aortic cross-clamping.
Examined correlations between enzyme levels and early postoperative outcomes.
Detected CK-MB activity in all patients during surgery, with peak CK-MB occurring before peak total CK.
Significant correlation between elevated CK-MB and prolonged durations of extracorporeal circulation (ECC >120 min) and aortic cross-clamping (AC >70 min).
No myocardial infarction observed postoperatively; ASAT recommended for evaluating myocardial injury in absence of CK-MB.

Structured PICO

Population

25 patients undergoing coronary bypass operations

Intervention

Coronary bypass surgery

Outcome

Postoperative serum activity levels of total creatine kinase (CK) and its isoenzyme CK-MBsurrogate

Postoperative CK-MB elevation correlates with the duration of extracorporeal circulation and aortic cross-clamping during coronary bypass surgery, and ASAT is a preferable alternative when CK-MB is unavailable for early evaluation of myocardial injury.

Cite This Study

Ström et al. (1979) studied this question.

synapsesocial.com/papers/6a71876df44fa9f079df4f62 https://doi.org/10.3109/14017437909101787

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Implication

CK-MB elevation may reflect ECC/AC duration rather than injury post-CABG; case report leaves open optimal enzyme for myocardial assessment.

Serum Enzymes with Special Reference to CK-MB Following Coronary Bypass Surgery

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Serum Enzymes with Special Reference to CK-MB Following Coronary Bypass Surgery

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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Also Consider