Why the study?
Does CRT-P provide comparable quality-of-life and survival benefits to CRT-D in patients with severe and worsening heart failure due to systolic LV dysfunction?
Does CRT-P provide comparable quality-of-life and survival benefits to CRT-D in patients with severe and worsening heart failure due to systolic LV dysfunction?
The authors propose that a clinical trial comparing CRT-P and CRT-D is needed to determine their relative cost-effectiveness and impact on quality of life and survival in patients with severe heart failure.
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Evidence gap precludes firm CRT-P vs CRT-D recommendations in severe HF; leaves open whether a dedicated RCT can resolve survival and cost questions.
Cengiz Ermiş (2006) studied this question.
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