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Pregnancy induces physiological changes including blood hypercoagulability, endothelial injury, and stasis that predispose to thrombus formation and pulmonary embolism.
During pregnancy the haemostatic system is progressively activated to prepare the haemostatic needs of delivery and postpartum.Blood hypercoagulability, endothelial injury and stasis of blood flow predispose to thrombus formation.Pulmonary embolism is a complication of venous thrombosis and is a leading cause of pregnancy related deaths at any trimester.It is extremely common disorder without specific clinical features.The physician is called to suspect the disorder and give a prompt diagnosis and therapy to avoid the lethal condition.Delays in pulmonary embolism diagnosis and therapy are common and represent an important issue.
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Irene M. Orfanoudaki (2019) conducted a review in Pulmonary embolism in pregnancy. Anticoagulation with low-molecular-weight heparin (LMWH) or unfractionated heparin (UFH) vs. Untreated pulmonary embolism or comparison between LMWH and UFH was evaluated.
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