The study demonstrates that muscle fiber type distribution varies within fascicles, with differences between border and internal regions being more pronounced in younger men.
Muscle biopsy interpretation requires fascicle location awareness; leaves open mechanisms of age-related fiber type homogenization.
The proportions of different fiber types (type 1 and type 2) on the borders of fascicles are shown to differ from the proportions internally. This finding is based on the analysis of a total of 245 fascicles from whole cross-sections of the vastus lateralis muscle from 13 men, aged from 26-80 years. Generally, the difference is more marked in the young than in the old. It is argued that the causes of this difference are likely to be local factors in the muscle.
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Sjöstróm et al. (1986) studied this question.
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