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December 1, 1982Acta Physiologica Scandinavica

The needle biopsy technique for fibre type determination in human skeletal muscle–a methodological study

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Population

34 healthy male subjects

Design

Other

Authors

EBEva BlomstrandKarolinska InstitutetBEBjörn EkblomPreventive Cardiology

Discussion

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Implication

May reduce fiber-typing error with same-site duplicates; leaves open standardization across clinical and research protocols.

Structured PICO

P
Population
34 healthy male subjects
I
Intervention
Repeated needle biopsies from the vastus lateralis muscle
O
Outcome
Variation in fibre type composition (type I, IIA, and IIB) between duplicate biopsiessurrogate

Taking two needle biopsies from the same muscle site significantly reduces methodological error in determining skeletal muscle fibre type composition.

Limitations

  • Classification between subgroups of type II-fibres was subjected to personal estimate

Cite This Study

Blomstrand et al. (1982) studied this question.

synapsesocial.com/papers/6a720c4e87f9210571287003https://doi.org/10.1111/j.1748-1716.1982.tb07163.x
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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Intramuscular variation of fiber types in the brachial biceps and the lateral vastus muscles of elderly men: How representative is a small biopsy sample?1982 · 69 citations
  2. 2THE SPECIFICITY OF THE HISTOCHEMICAL METHOD FOR ADENOSINE TRIPHOSPHATAS1955 · 1,219 citations