Key result
Small muscle biopsies fail to reliably assess fiber type grouping due to variation across sites.
Population
5 elderly men (autopsy samples of brachial biceps and lateral vastus muscles)
Comparison
Analysis of muscle fiber type distribution in… vs Analysis in large areas at nine sites
Design
Other
Authors
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Small needle biopsies may not reliably represent fiber type distribution in elderly men; leaves open optimal sampling methods for muscle histology research.
Observational (n=5)
Small needle biopsies may not reliably represent muscle fiber type distribution in the brachial biceps and lateral vastus muscles of elderly men.
Nygaard et al. (1982) reported an observational. Small biopsy sample (needle biopsy equivalent) vs. Large areas of muscle was evaluated on Distribution of muscle fiber types. Small muscle biopsy samples are not suited for analyzing fiber type grouping due to systematic variation in fiber type incidence across different muscle sites.
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