Amino acid sequence of a mouse myeloma immunoglobin heavy chain (MOPC 47 A) with a 100-residue deletion.
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Discussion
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Implication
Randomized trial investigates the amino acid sequence alterations in myeloma immunoglobulin.
Key Points
- To characterize the amino acid sequence of a specific mouse myeloma immunoglobulin heavy chain variant with a substantial deletion.
- Determined the amino acid sequence of the MOPC 47 A immunoglobulin heavy chain.
- Identified a 100-residue deletion in the sequence.
- The sequence revealed 46 distinct amino acids along with the described deletion.
- Alterations in sequence can impact immunoglobulin function.
Cite This Study
Robinson et al. (1979) studied this question.