A simple nomogram for adequate haemodialysis

This is the authors' abstract. We don't add key points for this paper.

The publishers wouldl like to apologise for an error that occured in the printing of the abstract by Dr van der Meulen et al. We republish below the abstract along with the correct accompanying figure. HD is adequate when 3 sessions per week result in a time-averaged concentration of urea (TACu) of ± 19 mmol/1. Determinants of TACu are dialyser clearance (K), dialysis time (t), volume of distribution (V), and daily protein intake (DPI). Assuming single-pool kinetics, sufficient DPI, and no residual diuresis; the relations between PREu and POSTu are: Kt/V = ln[(Postu/PreuUF/W] and DPI= [157*(Preu-Postu)]sol;(T3sol;l) + 0.176, where UF is ultrafiltrate, W postdialysis weight, and T3/1 the longest interval. From these equations a nomogram for DPI (curves) and domain of adequate HD (shaded area) can be made. Combining row Postu/Preywith WL i.e. UF as %W gives Kt/V.

Nomogram may aid hemodialysis adequacy assessment; leaves open prospective validation before clinical use.