The Revised QUADAS-2 Tool

Letters21 February 2012The Revised QUADAS-2 ToolSabine Schueler, MD, Georg M. Schuetz, MD, and Marc Dewey, MD, PhDSabine Schueler, MDFrom Charite–Universitaetsmedizin Berlin, Berlin 10117, Germany., Georg M. Schuetz, MDFrom Charite–Universitaetsmedizin Berlin, Berlin 10117, Germany., and Marc Dewey, MD, PhDFrom Charite–Universitaetsmedizin Berlin, Berlin 10117, Germany.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-156-4-201202210-00018 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:It was with great interest that we read the recent article by Whiting and colleagues (1) introducing the QUADAS-2 (Quality Assessment of Diagnostic Accuracy Studies) tool, a revision of the tool from 2003 (2). It is important that such pivotal methodological work about diagnostic review research is made widely available through publication in Annals of Internal Medicine.We would like to discuss some issues related to QUADAS-2, as some of them attracted our attention when reading the otherwise impressive article. First, in the original QUADAS tool (2), items 1 and 2 related to variability with the potential ...References1. Whiting PF, Rutjes AW, Westwood ME, Mallett S, Deeks JJ, Reitsma JB, et al; QUADAS-2 Group. QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies. Ann Intern Med. 2011;155:529-36. [PMID: 22007046] LinkGoogle Scholar2. Whiting P, Rutjes AW, Reitsma JB, Bossuyt PM, Kleijnen J. The development of QUADAS: a tool for the quality assessment of studies of diagnostic accuracy included in systematic reviews. BMC Med Res Methodol. 2003;3:25. [PMID: 14606960] CrossrefMedlineGoogle Scholar3. The Cochrane Collaboration. Glossary of Terms in The Cochrane Collaboration, Version 4.2.5; 2005. Accessed at www.cochrane.org/sites/default/files/uploads/glossary.pdf on 7 November 2011. Google Scholar4. Richardson WS, Wilson MC, Nishikawa J, Hayward RS. The well-built clinical question: a key to evidence-based decisions [Editorial]. ACP J Club. 1995;123:A12-3. [PMID: 7582737] LinkGoogle Scholar5. Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gøtzsche PC, Ioannidis JP, et al. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. Ann Intern Med. 2009;151:W65-94. [PMID: 19622512] LinkGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From Charite–Universitaetsmedizin Berlin, Berlin 10117, Germany.Disclosures: Dr. Dewey: Consultancy: Guerbet; Grants/grants pending (money to institution): European Regional Development Fund, German Research Foundation/German Federal Ministry of Education and Research, GE Healthcare, Bracco, Guerbet, Toshiba Medical Systems; Payment for development of educational presentations including service on speakers bureaus (money to institutions): Toshiba Medical Systems, Bayer-Schering, Guerbet, Cardiac MR Academy Berlin; Travel/accommodations expenses covered or reimbursed (money to institutions): Toshiba Medical Systems, Bayer-Schering; Other (money to institution): Course Director for Cardiac CT Hands-on Courses at Charite in Berlin, institutional master research agreements with Siemens Medical Solutions, Philips Medical Systems, and Toshiba Medical Systems; Other: Book author for Springer titles Coronary CT Angiography (2009) and Cardiac CT (2011). PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoThe PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and Elaboration Alessandro Liberati , Douglas G. Altman , Jennifer Tetzlaff , Cynthia Mulrow , Peter C. Gøtzsche , John P.A. Ioannidis , Mike Clarke , P. J. Devereaux , Jos Kleijnen , and David Moher QUADAS-2: A Revised Tool for the Quality Assessment of Diagnostic Accuracy Studies Penny F. Whiting , Anne W.S. Rutjes , Marie E. Westwood , Susan Mallett , Jonathan J. Deeks , Johannes B. Reitsma , Mariska M.G. Leeflang , Jonathan A.C. Sterne , Patrick M.M. Bossuyt , and The Revised QUADAS-2 Tool Penny F. Whiting and Jonathan A.C. 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