March 1, 1993Journal of Magnetic Resonance Imaging
Accuracy and precision of MR velocity mapping in measurement of stenotic cross‐sectional area, flow rate, and pressure gradient
Why the study?
Does MR velocity mapping accurately measure stenotic cross-sectional area, flow rate, and pressure gradient in vitro and in vivo?
Population
In vitro model with five stenoses and a single patient with aortic stenosis.
Comparison
Magnetic resonance velocity mapping performed… vs Manometer measurements and heart catheterization.
Design
Preclinical
Authors
Discussion
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Implication
May aid preclinical stenosis research; leaves open human validation before clinical use.
Structured PICO
Does MR velocity mapping accurately measure stenotic cross-sectional area, flow rate, and pressure gradient in vitro and in vivo?
P
Population
In vitro model with five stenoses (central orifice area ranging from 17 to 176 mm2) and a single patient with aortic stenosis.
I
Intervention
Magnetic resonance (MR) velocity mapping performed perpendicular to the stenotic jet.
C
Comparator
Manometer measurements (for pressure gradient in vitro) and heart catheterization (for the patient).
O
Outcome
Accuracy, precision, and error of stenotic cross-sectional area, flow rate, and pressure gradient measurements.surrogate
MR velocity mapping provides accurate and precise measurements of stenotic cross-sectional area, flow rate, and pressure gradient, though the modified Bernoulli equation is limited to specific stenosis sizes.
Limitations
- The modification of the Bernoulli equation limited its reliability to stenoses with areas of 35-113 mm2.
Cite This Study
Søndergaard et al. (1993) studied this question.