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This study aims to define the risk of immediate complications from intravenous contrast in computed tomography imaging.

Immediate Complications of Intravenous Contrast for Computed Tomography Imaging in the Outpatient Setting Are Rare

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This study aims to define the risk of immediate complications from intravenous contrast in computed tomography imaging.
Prospective, consecutive cohort study of patients receiving computed tomography with intravenous contrast in the ED.
Monitoring for complications within 1 week post-contrast administration using predefined definitions.
Assessment of both minor and severe complications requiring medical or surgical intervention.
Out of 633 patients, only five (0.8%, 95% CI 0.3% to 1.8%) reported immediate complications, all classified as minor.
No severe complications, such as anaphylactoid shock or acute pulmonary edema, occurred in any patient.
The frequency of severe immediate complications from CECT is less than 1%, and mild complications are under 2%.

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Prospective cohort study evaluates immediate complications in patients undergoing CT imaging, suggesting low risk.

Mitchell et al. (2011) studied this question.

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