This case report highlights the occurrence of subacute doxorubicin-induced cardiomyopathy in a patient without prior cardiac risk factors.
May prompt closer cardiac monitoring during doxorubicin therapy even without risk factors; leaves open incidence, mechanisms, and prevention strategies.
Adriamycin is an antineoplastic agent used in a wide variety of malignancies. Its use is limited because of a cumulative, dose-dependent irreversible cardiomyopathy. We report a case of adriamycin-induced cardiomyopathy, after he had undergone chemotherapy for Hodgin lymphoma. The patient had no cardiac risk factors, and neither laboratory nor imaging findings suggested myocarditis or dilated cardiomyopathy. Echocardiographic findings and differential diagnosis led us to attribute his condition to subacute doxorubicin-induced cardiomyopathy. J Med Cases. 2015;6(5):226-228 doi: http://dx.doi.org/10.14740/jmc2132w
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Marios Lemoniatis (2015) studied this question.
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