October 1, 1995Anesthesia & Analgesia

Sevoflurane for Outpatient Anesthesia

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Why the study?

Does sevoflurane improve induction and recovery times compared to propofol in healthy outpatients undergoing ambulatory surgery?

Population

146 healthy outpatients undergoing ambulatory surgery

Comparison

Sevoflurane for induction and maintenance, or… vs Propofol induction and maintenance. All patients…

Design

Other

Follow-up

until discharge

Authors

BFBrian FredmanTel Aviv University MNMichael H. NathansonUniversidade Federal de Minas Gerais ISIan SmithUniversity of Miami

Discussion

Member takes

Implication

Sevoflurane acceptable alternative despite slower induction in outpatients; Level 5 data leaves open optimal agent selection in randomized trials.

Structured PICO

Does sevoflurane improve induction and recovery times compared to propofol in healthy outpatients undergoing ambulatory surgery?

Population

146 healthy outpatients undergoing ambulatory surgery

Intervention

Sevoflurane for induction (1%-4% end-tidal) and maintenance, or propofol induction (1.5-2.0 mg/kg IV) with sevoflurane maintenance (1%-2% end-tidal). All patients received N2O 60% in oxygen, fentanyl 2-3 micrograms/kg IV, and vecuronium 0.1 mg/kg IV.

Comparator

Propofol induction (1.5-2.0 mg/kg IV) and maintenance (75-160 micrograms.kg-1.min-1 IV). All patients received N2O 60% in oxygen, fentanyl 2-3 micrograms/kg IV, and vecuronium 0.1 mg/kg IV.

Outcome

Induction time, recovery times, and discharge times

Sevoflurane is an acceptable alternative to propofol for induction and maintenance of outpatient anesthesia, despite a slower induction time and higher incidence of postoperative emesis.

Cite This Study

Fredman et al. (1995) studied this question.

synapsesocial.com/papers/6a719aea8031ec7bb1dd0b1e https://doi.org/10.1097/00000539-199510000-00028

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Implication

Sevoflurane acceptable alternative despite slower induction in outpatients; Level 5 data leaves open optimal agent selection in randomized trials.

Sevoflurane for Outpatient Anesthesia

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Sevoflurane for Outpatient Anesthesia

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider