What question did this study set out to answer?

This research aims to compare the recovery characteristics of sevoflurane and desflurane in outpatient anesthesia.

December 1, 1995Anesthesia & Analgesia

Sevoflurane Versus Desflurane for Outpatient Anesthesia

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Why the study?

Does sevoflurane compared to desflurane affect recovery characteristics in healthy women undergoing outpatient laparoscopic sterilization?

Population

42 healthy, unpremedicated women undergoing laparoscopic sterilization procedures

Comparison

Sevoflurane 1%-2% with 60% nitrous oxide in… vs Desflurane 3%-6% with 60% nitrous oxide in…

Design

RCT

Follow-up

Recovery period (up to discharge)

Authors

MNMichael H. NathansonUniversidade Federal de Minas Gerais BFBrian FredmanTel Aviv University ISIan SmithUniversity of Miami

Discussion

Member takes

Implication

Similar discharge times despite faster emergence with desflurane; confirms either agent acceptable for outpatient laparoscopy.

Key Points

This research aims to compare the recovery characteristics of sevoflurane and desflurane in outpatient anesthesia.
42 healthy women were randomized to receive either desflurane or sevoflurane during anesthesia for laparoscopic sterilization.
Key measures included heart rate, mean arterial pressure, visual analog scales (VAS), and digit-symbol substitution test (DSST) during recovery.
Anesthesia was maintained with inhaled agents alongside propofol, fentanyl, and vecuronium.
Desflurane resulted in faster emergence from anesthesia (4.8 +/- 2.4 min vs 7.8 +/- 3.8 min) and shorter extubation time (5.1 +/- 2.2 min vs 8.2 +/- 4.2 min) compared to sevoflurane.
Heart rate values were lower in the sevoflurane group during the induction-to-incision period; however, overall HR and MAP were comparable.
Cognitive function and discharge times post-anesthesia were similar between both groups.

Structured PICO

Does sevoflurane compared to desflurane affect recovery characteristics in healthy women undergoing outpatient laparoscopic sterilization?

Population

42 healthy, unpremedicated women undergoing laparoscopic sterilization procedures

Intervention

Sevoflurane 1%-2% with 60% nitrous oxide in oxygen for maintenance of anesthesia

Comparator

Desflurane 3%-6% with 60% nitrous oxide in oxygen for maintenance of anesthesia. Both groups received propofol induction (1.5-2.0 mg/kg), fentanyl, and vecuronium.

Outcome

Recovery characteristics including emergence time, time to extubation, intermediate recovery times, postoperative VAS and DSST scores, and side effectssurrogate

Although sevoflurane is associated with slower emergence than desflurane, overall recovery of cognitive function and discharge times are similar, making it an acceptable alternative for outpatient anesthesia.

Cite This Study

Nathanson et al. (1995) studied this question.

synapsesocial.com/papers/6a706b7935aa2c282ce1bce4 https://doi.org/10.1097/00000539-199512000-00012

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Sevoflurane Versus Desflurane for Outpatient Anesthesia

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Sevoflurane Versus Desflurane for Outpatient Anesthesia

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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