Why the study?
Do levels of antibodies against oxidized cardiolipin (aOxCL) predict the risk of cardiovascular disease in 60-year-olds?
Population
844 60-year-olds from Stockholm County identified from a screening cohort of 4,232 individuals.
Comparison
Levels of IgM and IgG antibodies to oxidized… vs Highest quartile of aOxCL levels (reference group)
Design
Case-control
Follow-up
5-7 years
Authors
Loading...
IgM aOxCL may mark elevated CVD risk in older adults; leaves open incremental prediction and prospective validation before clinical use.
Do levels of antibodies against oxidized cardiolipin (aOxCL) predict the risk of cardiovascular disease in 60-year-olds?
Low levels of IgM antibodies to oxidized cardiolipin are associated with an increased risk of cardiovascular disease, while high levels are associated with decreased risk, identifying aOxCL as a novel biomarker.
Su et al. (2013) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: