Why the study?
Does intermittent social defeat stress alter cardiac electrophysiological properties in adult male rats?
Population
Adult male wild-type rats (n=23)
Comparison
Intermittent social defeat stress vs Empty cage exposure (control)
Design
Preclinical
Follow-up
9 days after last exposure
Authors
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Hypothesis-generating for stress-induced proarrhythmic remodeling in rats; human relevance remains to be determined.
Does intermittent social defeat stress alter cardiac electrophysiological properties in adult male rats?
Intermittent social stress in rats induces depression-like symptoms and proarrhythmic electrical remodeling, including reduced refractoriness and impaired conduction.
Carnevali et al. (2012) studied this question.
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