Why the study?
Does pre-operative treatment with ACEIs affect haemodynamic parameters and vasoconstrictor requirements in patients undergoing off-pump coronary artery bypass surgery?
Population
80 patients undergoing off-pump coronary artery bypass surgery (OPCAB)
Comparison
Pre-operative treatment with… vs No pre-operative treatment with ACEIs
Design
Cohort
Follow-up
Intraoperative
Authors
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Preoperative ACEI use was associated with greater noradrenaline needs during OM anastomosis in OPCAB; leaves open whether discontinuation improves outcomes.
Does pre-operative treatment with ACEIs affect haemodynamic parameters and vasoconstrictor requirements in patients undergoing off-pump coronary artery bypass surgery?
Pre-operative ACE inhibitor use is associated with increased intraoperative vasoconstrictor requirements to maintain blood pressure during off-pump coronary artery bypass surgery.
Lee et al. (2005) studied this question.
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