Why the study?
To compare the incidence of hypotension after intrathecal administration of hyperbaric bupivacaine and fentanyl in two different syringes versus standard injection of mixed fentanyl with hyperbaric bupivacaine.
Does intrathecal administration of hyperbaric bupivacaine and fentanyl in two different syringes reduce hypotension in parturients undergoing elective cesarean section?
Does intrathecal administration of hyperbaric bupivacaine and fentanyl in two different syringes reduce hypotension in parturients undergoing elective cesarean section?
Administering hyperbaric bupivacaine and fentanyl in separate syringes during spinal anesthesia for cesarean section significantly reduces the early drop in blood pressure compared to mixing them in a single syringe.
Two-syringe technique may reduce hypotension in cesarean spinal anesthesia; leaves open need for randomized confirmation before practice change.
Aims: To compare the incidence of hypotension after intrathecal administration of hyperbaric bupivacaine and fentanyl in two different syringes against standard injection of mixed fentanyl with hyperbaric bupivacaine. Methods: This was a prospective comparative study conducted in 174 parturients undergoing elective caesarean section at Paropakar Maternity & Women’s Hospital. Hemodynamic effects and characteristics of block were monitored and recorded and compared between the two groups, group S (single syringe) and group D (double syringe). Results: The incidence of hypotension was almost similar in the two groups but the drop in systolic blood pressure and mean arterial pressure at 5 minutes and 7.5 minutes after subarachnoid block was significant in group S as compared to group D (p<0.005 and p<0.005 respectively). Conclusion: Hyperbaric bupivacaine with fentanyl, which when injected separately without mixing, is associated with lesser incidence of hypotension following subarachnoid block.
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Shrestha et al. (2022) studied this question.
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