Inguinal Lymph Node Squamous Cell Carcinoma of Unknown Primary Site: A Case Report

Carcinoma of unknown primary site (CUP) accounts for approximately 3% to 5% of all cancers [13]. However when disseminated, it is one of the leading causes of cancer related mortality worldwide. Autopsy series have shown that in cases of CUP, the lung is the most common site of primary followed by liver, pancreas and gastrointestinal tract [4]. Approximately 10-40% of these patients have metastasis confined to the regional lymph nodes whereas in the rest, internal organs are involved [5]. In the former subgroup, cervical nodes are the most common nodal basins followed by axillary nodes. In general, treatment of CUP is guided by the suspected origin of the primary carcinoma and hence an extensive diagnostic work up is essential. CUP involving the inguinal nodes is rare accounting for only 1% to 3.5% of this subgroup of patients [6,7]. We are presenting a case of inguinal node Squamous cell carcinoma deposit of unknown primary site which was treated with surgery and chemotherapy. Abstract