Why the study?
Brugada syndrome is predominantly reported in males, and among South-East Asian countries, only one previous case had been reported from Bangladesh, which was also in a male patient.
This case report highlights a rare presentation of Brugada syndrome in a female patient from Bangladesh, a demographic where the condition is highly uncommon.
Case illustrates Brugada EKG diagnosis; leaves open larger studies on geographic and sex-specific prevalence.
Brugada syndrome is inherited in an autosomal dominant pattern which is associated with ventricular fibrillation and sudden cardiac death in a patient with structurally normal heart. The diagnosis is clinched on characteristic EKG pattern of >2 mm ST segment elevation followed by negative T wave in right precordial leads V1,2 either occurring spontaneously or with pharmacological provocation with a sodium channel blocker. Prevalence of this disease varies by geographic location and sex with highest preponderance in South East Asian countries and in males. Among South-East Asian countries, there has been only one case report so far from Bangladesh and that too in a male patient. We present a case of female patient from Bangladesh with Brugada syndrome. We also report an association of Autism with Brugada syndrome in patient’s only female child. Cardiovasc j 2022; 15(1): 86-87
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Roychoudhury et al. (2022) studied this question.
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