March 1, 1992Developmental Dynamics

Expression of sarcomeric myosin in the presumptive myocardium of chicken embryos occurs within six hours of myocyte commitment

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Population

Chicken embryos (stages 6-10)

Design

Preclinical

Authors

YHYong-Woon HanNagoya City University JDJames E. DennisCentre for Immunity, Infection and Evolution LCLeona Cohen‐GouldCornell University

Discussion

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Implication

Early myosin precedes heartbeat in chick embryos; extends avian developmental timeline but leaves translational relevance to mammals open.

Structured PICO

Population

Chicken embryos (stages 6-10)

Intervention

Immunocytochemical staining with monoclonal antibody MF20

Outcome

Distribution and timing of sarcomeric myosin heavy chain (MyHC) expressionsurrogate

This study demonstrates that sarcomeric myosin expression in chicken embryos begins as early as stage 7, prior to the onset of the heartbeat and sarcomeric organization.

Cite This Study

Han et al. (1992) studied this question.

synapsesocial.com/papers/6a71a981ac440176ef2a46ea https://doi.org/10.1002/aja.1001930306

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Implication

Early myosin precedes heartbeat in chick embryos; extends avian developmental timeline but leaves translational relevance to mammals open.

Expression of sarcomeric myosin in the presumptive myocardium of chicken embryos occurs within six hours of myocyte commitment

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Expression of sarcomeric myosin in the presumptive myocardium of chicken embryos occurs within six hours of myocyte commitment

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider