Key result
Increased systolic blood pressure was independently associated with diabetic retinopathy in both hypertensive (aOR 1.020, p<0.001) and normotensive (aOR 1.019, p=0.018) patients with type 2 diabetes.
Why the study?
Associations between blood pressure and diabetic retinopathy risk in diabetic patients with normal blood pressure have received inadequate attention, potentially leading to clinical inertia.
Is increased systolic blood pressure associated with diabetic retinopathy in both hypertensive and normotensive patients with type 2 diabetes?
Observational (n=2,510)
Is increased systolic blood pressure associated with diabetic retinopathy in both hypertensive and normotensive patients with type 2 diabetes?
Effect estimate: aOR 1.020 (hypertensives) and aOR 1.019 (normotensives)
p-value: p=<0.001 (hypertensives) and 0.018 (normotensives)
Higher systolic blood pressure is associated with an increased risk of diabetic retinopathy in patients with type 2 diabetes, even among those with blood pressure in the normal range.
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May warrant SBP monitoring in normotensive T2DM; leaves open whether lowering SBP prevents retinopathy.
Li et al. (2021) conducted an observational in Type 2 diabetes (n=2,510). Systolic blood pressure was evaluated on Diabetic retinopathy (aOR 1.020 (hypertensives) and aOR 1.019 (normotensives), p=<0.001 (hypertensives) and 0.018 (normotensives)). Increased systolic blood pressure was independently associated with diabetic retinopathy in both hypertensive (aOR 1.020, p<0.001) and normotensive (aOR 1.019, p=0.018) patients with type 2 diabetes.
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