Key result
Mean systolic blood pressure among hypertensive patients significantly decreased from 134.0 mm Hg in 2008 to 132.6 mm Hg in 2011, associated with treatment using a larger number and higher doses of antihypertensive agents.
Cross-Sectional (n=9,982)
Absolute Event Rate: 132.6% vs 134%
p-value: p=<0.001
Blood pressure control in Japanese hypertensive patients improved from 2008 to 2011, driven by more aggressive use of antihypertensive agents.
Supports intensified antihypertensive regimens for BP control in Japanese patients; leaves open causality and generalizability.
We performed cross-sectional surveys to investigate changes in clinical practices regarding blood-pressure control in patients with hypertension from 2008 through 2011. Questionnaires regarding the care of patients with hypertension were mailed to members of the Kanagawa Physicians Association in Kanagawa Prefecture, Japan. Data were obtained on 675 patients in 2008, 332 in 2009, and 1,076 in 2011. The mean systolic blood pressure (BP) was significantly lower in 2011 than in 2008 (132.2±11.9 mm Hg versus 134.6±10.6 mm Hg). The office-measured target BP, according to the 2009 guidelines of the Japanese Society of Hypertension for the management of patients with hypertension, was achieved in 53.9% of patients in 2008, 55.1% in 2009, and 57.1% in 2011. In nonelderly patients (younger than 65 years), the achievement rate was significantly greater in 2011 (41.2%) than in 2008 (23.6%). This analysis showed that the factor most significantly associated with a decrease in office-measured BP was treatment with a larger number and higher doses of antihypertensive agents. To investigate changes in clinical practices according to the guidelines, further follow-up surveys are necessary.
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Hatori et al. (2014) conducted a cross-sectional in Hypertension (n=9,982). Clinical practice in 2011 vs. Clinical practice in 2008 was evaluated on Mean systolic blood pressure (p=<0.001). Mean systolic blood pressure among hypertensive patients significantly decreased from 134.0 mm Hg in 2008 to 132.6 mm Hg in 2011, associated with treatment using a larger number and higher doses of antihypertensive agents.
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