Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
May 31, 2023Open Access

The prevalence of Type-A aortic dissection in regional New South Wales was 1.47 per 100,000 with a mortality rate of 2.12 per 100,000, which was lower than expected compared to previous global studies.

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Acute aortic dissection is a time-critical surgical emergency, but no prior studies had examined Type-A AD in regional Australia, which faces large travel distances and limited resources.

Population

Population of the Hunter New England health district in regional New South Wales, Australia

Design

Retrospective epidemiological analysis

Key result

The prevalence of Type-A aortic dissection in regional New South Wales was 1.47 per 100,000 with a mortality rate of 2.12 per 100,000, which was lower than expected compared to previous global studies.

Authors

ARAyeshmanthe RathnayakeOCOlivia H. ChangTNTakuya Narita

Discussion

Loading...

Member takes

Overview

Lower regional Type A dissection prevalence and mortality may reflect underdetection; leaves open need for prospective validation of geographic variation.

Study Design

Type

Observational (n=122)

Multicenter

No

Structured PICO

P
Population
122 patients with acute Type-A aortic dissection in regional New South Wales, Australia, evaluated retrospectively over a 10-year period to determine epidemiological trends.
O
Outcome
Prevalence and mortalityhard clinical

Main Result

Effect estimate: Prevalence 1.47 per 100,000; Mortality 2.12 per 100,000

In regional Australia, Type-A aortic dissection has a prevalence of 1.47 per 100,000 and a 30-day mortality of 14.75%, with combined smoking and hypertension significantly increasing mortality risk.

Limitations

  • Small study sample size
  • Retrospective cohort design open to selection bias
  • Potential for missing records and misclassification of data
  • Small sample size
  • Retrospective cohort study open to selection bias
  • Missing records
  • Misclassification of data

Cite This Study

Rathnayake et al. (2023) conducted an observational in Acute Type-A Aortic Dissection (n=122). Acute Type-A Aortic Dissection was evaluated on Prevalence and mortality (Prevalence 1.47 per 100,000; Mortality 2.12 per 100,000). The prevalence of Type-A aortic dissection in regional New South Wales was 1.47 per 100,000 with a mortality rate of 2.12 per 100,000, which was lower than expected compared to previous global studies.

synapsesocial.com/papers/6a71b240f44fa9f079df6e81https://doi.org/10.21203/rs.3.rs-2987473/v1
View Full Paper
Ask AI
Bookmark
Share