Perioperative anaphylaxis, a challenge to anaesthetists: A report of two cases

Perioperative anaphylaxis is a life-threatening, immediate hypersensitivity reaction, which occurs rarely, but carries a high rate of morbidity and mortality. Multiple causative factors have been attributed, where antibiotics and neuromuscular blockers are among the leading causes. Diagnosis is challenging due to the overlapping physiological alterations during anaesthesia and polypharmacy. This case series presents two cases of anaphylactic shock, due to different aetiologies during the perioperative period, which were managed successfully Keywords: anaphylaxis; perioperative anaphylaxis; neuromuscular blockers; methylprednisolone; nap 6.