Key result
Idiopathic sudden sensorineural hearing loss was associated with altered autonomic regulation, discriminating patients from controls with an AUC of 95.5, 90.9% sensitivity, and 88.9% specificity.
Why the study?
Do patients with idiopathic sudden sensorineural hearing loss have altered autonomic regulation compared to normal-hearing controls?
Population
23 adult patients with idiopathic sudden sensorineural hearing loss and 10 normal-hearing control patients…
Comparison
None (observational study) vs 10 normal-hearing control patients without ISSHL…
Design
Cohort
Authors
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Altered autonomic regulation in ISSNHL may support vascular hypotheses; leaves open diagnostic utility pending prospective validation.
Cohort (n=33)
No
Do patients with idiopathic sudden sensorineural hearing loss have altered autonomic regulation compared to normal-hearing controls?
Effect estimate: AUC 95.5
Patients with idiopathic sudden sensorineural hearing loss show altered autonomic regulation and cardiovascular coupling, suggesting a potential vascular pathogenesis.
Schulz et al. (2014) conducted a cohort in Idiopathic sudden sensorineural hearing loss (ISSHL) (n=33). Idiopathic sudden sensorineural hearing loss (ISSHL) vs. Normal-hearing control patients without ISSHL was evaluated on Multivariate discrimination between ISSHL and CON based on autonomic regulation (AUC 95.5). Idiopathic sudden sensorineural hearing loss was associated with altered autonomic regulation, discriminating patients from controls with an AUC of 95.5, 90.9% sensitivity, and 88.9% specificity.
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