Key result
Aortic valve repair using autologous pericardial patch plasty showed similar 5-year freedom from aortic regurgitation ≥ II degrees compared to repair without additional material (87.8% vs 95.0%; p=0.21).
Why the study?
Does aortic valve repair using autologous pericardial patch plasty provide comparable outcomes to repair without additional material in patients undergoing isolated aortic valve repair?
Cohort (n=84)
Does aortic valve repair using autologous pericardial patch plasty provide comparable outcomes to repair without additional material in patients undergoing isolated aortic valve repair?
Absolute Event Rate: 87.8% vs 95%
p-value: p=0.21
Aortic valve repair using autologous pericardial patch plasty yields satisfactory functional results and comparable freedom from reoperation and significant regurgitation compared to repair without additional material.
Should not yet change aortic valve repair practice; leaves open randomized confirmation of long-term durability.
INTRODUCTION: Isolated aortic valve repair (AVR) has been gaining increasing interest in recent times. Results of isolated aortic valve repair have been reported to be variable. Various techniques have been utilized. We analyzed our experience with isolated valve repair using autologous pericardial patch plasty and compared the results to an age-matched collective with aortic valve repair without the use of additional material. METHODS: Between January 1997 and June 2005, pericardial patch plasty of the aortic valve was performed in 42 patients (PATCH). During the same period, 42 patients after AVR without the use of additional material were age matched (NO-PATCH). Mean age in both groups was 52 years with a majority of male patients (PATCH ratio, 3.7:1; NO-PATCH ratio, 5:1). Valve anatomy was similar in both groups. All patients were followed by echocardiography for a cumulative follow-up of 2341 patient months (mean 28+/-23 months). RESULTS: No patient died in the hospital in neither group. The average systolic gradient was 5.9+/-2.2 mmHg in PATCH and 4.8+/-2.1 mmHg in NO-PATCH; p=0.17). Freedom from aortic regurgitation > or = II degrees was 87.8% in PATCH and 95.0% in NO-PATCH after 5 years (p=0.21). Freedom from reoperation was 97.6% in PATCH and 97.4% in NO-PATCH (p=0.96). CONCLUSIONS: Aortic regurgitation can be treated effectively by aortic valve repair using pericardial patch plasty. The functional results are satisfactory. With the application of this technique also more complex pathologies of the aortic valve can be addressed adequately thus extending the concept of valve preservation in patients with aortic regurgitation.
No takes yet. Share an insight, caveat, or question.
LAUSBERG et al. (2006) conducted a cohort in Aortic regurgitation (n=84). Aortic valve repair using autologous pericardial patch plasty vs. Aortic valve repair without additional material was evaluated on Freedom from aortic regurgitation >= II degrees after 5 years (p=0.21). Aortic valve repair using autologous pericardial patch plasty showed similar 5-year freedom from aortic regurgitation ≥ II degrees compared to repair without additional material (87.8% vs 95.0%; p=0.21).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: