Key result
Myogenic tone in peripheral resistance arteries and arterioles is regulated by multiple complex mechanisms including G-protein-coupled receptors, various ion channels, and protein kinases.
Why the study?
Despite the central importance of resistance artery and arteriolar myogenic tone in cardiovascular physiology and pathophysiology, understanding of the underlying signaling pathways remains incomplete.
Provides a comprehensive overview of the signaling pathways underlying myogenic tone in peripheral resistance arteries, emphasizing areas where physiological consensus is lacking.
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Underscores multifactorial vascular control; leaves open dominant pathway identification for hypertension therapies.
William F. Jackson (2021) conducted a review in Myogenic tone in peripheral resistance arteries and arterioles. Myogenic tone in peripheral resistance arteries and arterioles is regulated by multiple complex mechanisms including G-protein-coupled receptors, various ion channels, and protein kinases.
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