Key result
Patients with hypertension had a significantly higher cardio-ankle vascular index compared to non-hypertensive patients (8.73 vs 8.27, p < 0.001), while no significant independent correlation was observed between the index and triglyceride levels.
Why the study?
The cardio-ankle vascular index is a new indicator for arteriosclerosis, and this study investigated its relationship with lipid levels in patients with hypertension in a real clinical environment.
Cross-Sectional (n=2,656)
Yes
Absolute Event Rate: 8.73% vs 8.27%
p-value: p=< 0.001
The cardio-ankle vascular index (CAVI) is significantly elevated in patients with hypertension and is independently associated with multiple metabolic risk factors, though not directly with triglycerides.
Aim: The cardio-ankle vascular index (CAVI) is a new evaluation indicator for arteriosclerosis. This study investigated the relationship between the CAVI and lipid levels in patients with hypertension in a real clinical environment. Methods: This descriptive study enrolled 2,656 patients (male/female: 1,016/1,640) from the Outpatient Department of Vascular Medicine of Peking University Shougang Hospital and Jinding Street Community Health Service Center. CAVI was measured using a VaseraVS-1000 vascular screening system (Fukuda Denshi, Tokyo, Japan). Results: Age, body mass index (BMI), waist circumference, hip circumference, CAVI, systolic blood pressure (SBP), diastolic blood pressure (DBP), creatinine, fasting plasma glucose (FPG), uric acid (UA), hypersensitive C-reactive protein (hs-CRP), homocysteine, HbA1c, and triglyceride (TG) were significantly higher in the hypertension group than in the non-hypertension group. The levels of total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C) were significantly lower in the hypertension group than in the non-hypertension group. The CAVI value was significantly higher in patients with hypertriglyceridemia and normal LDL-C than in those with normal TG and hyper-LDL-C. Age, waist circumference, UA, FPG, HDL-C, hs-CRP, HbA1c, BMI, SBP, and DBP were independently associated with CAVI in all patients. Beta blockers were negatively correlated with CAVI (β = –0.411, P = 0.011). Sex (male) and history of hypertension and diabetes mellitus were positively correlated with CAVI (β = 0.419, P < 0.001; β = 0.247, P = 0.011; β = 0.638, P < 0.001; respectively). Conclusions: The CAVI was significantly higher in patients with hypertension and exhibited differences based on sex. Although we did not find a significant correlation between CAVI and TG, it remains crucial to maintain blood pressure to prevent the development of arteriosclerosis.
No takes yet. Share an insight, caveat, or question.
Liu et al. (2024) conducted a cross-sectional in Hypertension (n=2,656). Hypertension vs. Non-hypertension was evaluated on Cardio-ankle vascular index (CAVI) (p=< 0.001). Patients with hypertension had a significantly higher cardio-ankle vascular index compared to non-hypertensive patients (8.73 vs 8.27, p < 0.001), while no significant independent correlation was observed between the index and triglyceride levels.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: