Key result
Uncontrolled hypertension under drug treatment in men was associated with a higher prevalence of musculoskeletal complaints (adjusted RR 1.78; 95% CI 1.11-2.86).
Why the study?
Is hypertension associated with musculoskeletal complaints in a population-based sample?
Cross-Sectional (n=1,858)
Is hypertension associated with musculoskeletal complaints in a population-based sample?
Uncontrolled hypertension under drug treatment in men is associated with chronic musculoskeletal complaints, but hypertension itself does not appear to be a direct risk or protective factor.
Treated uncontrolled hypertension in men links to more musculoskeletal complaints; leaves open direct causality or confounding in cross-sectional data.
OBJECTIVE: To investigate the association between hypertension and musculoskeletal complaints among men and women selected by a population-based sample. METHODS: A cross-sectional study, with participants selected using a multistage sampling procedure and interviewed at home, was conducted to investigate the association between hypertension and musculoskeletal complaints. Hypertension was defined by the average of four measurements of blood pressure (BP) at least 140/90 mmHg or use of BP-lowering drugs. Musculoskeletal complaints in the 3 months before the interview were investigated by a structured questionnaire. RESULTS: Among 1858 participants, 58% were women, 64% were 18-49 years old, and 45% had up to 8 years of education. The prevalence of musculoskeletal complaint was 33% [95% confidence interval (CI) 30-36] and of hypertension was 34% (95% CI 32-37). Men and women with hypertension had higher prevalence of musculoskeletal complaint, which was no longer significant in women after adjustment for age, educational level, skin color, BMI, physical inactivity, diabetes mellitus, alcohol consumption, smoking and history of cardiovascular disease. Hypertensive men with uncontrolled hypertension using BP agents had higher prevalence of musculoskeletal complaint (adjusted risk ratio = 1.78; 95% CI 1.11-2.86). CONCLUSIONS: Chronic musculoskeletal complaints are more frequent in men with uncontrolled hypertension under drug treatment. The absence of association in women and in hypertensive men not taking BP drugs suggest that hypertension is not a risk or protection against musculoskeletal complaints.
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Kerkhoff et al. (2012) conducted a cross-sectional in Hypertension and musculoskeletal complaints (n=1,858). Hypertension vs. No hypertension was evaluated on Musculoskeletal complaints in the 3 months before the interview (adjusted RR 1.78, 95% CI 1.11-2.86). Uncontrolled hypertension under drug treatment in men was associated with a higher prevalence of musculoskeletal complaints (adjusted RR 1.78; 95% CI 1.11-2.86).
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