Key result
In-hospital mortality and cumulative mortality were not significantly different between heart failure patients with reduced versus non-reduced ejection fraction (P=0.797 and P=0.259, respectively).
Why the study?
Does heart failure with reduced ejection fraction (LVEF < 40%) compared to non-reduced ejection fraction (LVEF ≥ 40%) affect mortality in hospitalized heart failure patients?
Population
1,182 consecutive patients hospitalized with heart failure at a single center
Comparison
Heart failure with reduced ejection fraction vs Heart failure with non-reduced ejection fraction
Design
Cohort
Follow-up
median 23.7 months
Authors
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Should not yet guide EF-based risk stratification; leaves open phenotype-specific effects in prospective cohorts.
Cohort (n=1,182)
No
Does heart failure with reduced ejection fraction (LVEF < 40%) compared to non-reduced ejection fraction (LVEF ≥ 40%) affect mortality in hospitalized heart failure patients?
p-value: p=0.259 for cumulative mortality
Despite significant differences in clinical characteristics and comorbidities, patients hospitalized with HFrEF and non-HFrEF have similar in-hospital and cumulative mortality.
Zhou et al. (2018) conducted a cohort in Heart failure (n=1,182). Reduced ejection fraction (LVEF<40%) vs. Non-reduced ejection fraction (LVEF≥40%) was evaluated on In-hospital death and cumulative mortality (p=0.259 for cumulative mortality). In-hospital mortality and cumulative mortality were not significantly different between heart failure patients with reduced versus non-reduced ejection fraction (P=0.797 and P=0.259, respectively).
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