The Q-PULS extracorporeal model allows for the simulation of physiological parameters in explanted porcine hearts to test mitral valve repair techniques, potentially reducing the need for live animal experiments.
Background: Inventing new surgical procedures is demanding. A computer-controlled extracorporeal circulation system allows for testing of an explanted porcine heart simulating a variety of physiological and functional parameters. Mitral valve function can be assessed before and after induced valve insufficiency and after valve repair. Accordingly, technique and instruments can be modified in the early stages of prototype development.
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Ostovar et al. (2018) studied this question.
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