What question did this study set out to answer?

To investigate albumin excretion and prevalence of albuminuria in hypertensive versus normotensive individuals.

May 1, 1996Journal of Hypertension

Albuminuria in normotensive and hypertensive individuals attending offices of general practitioners

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Population

1,006 individuals attending 5 general practitioner offices, comprising 631 hypertensive patients and 375…

Design

Cross-sectional

Authors

DMDirk H mer DFDanilo FliserSaarland University HKHans P. Klimm

Discussion

Member takes

Implication

Albuminuria prevalence rises modestly with hypertension and diabetes; leaves open whether screening improves outcomes in prospective cohorts.

Key Points

To investigate albumin excretion and prevalence of albuminuria in hypertensive versus normotensive individuals.
Examined morning urine of 631 hypertensive and 375 normotensive individuals attending general practitioners.
Used kinetic nephrelometry to assess urinary albumin excretion.
Conducted multivariate regression analysis to explore correlations with confounding variables.
Median albumin excretion was 4.3 micrograms/ml in normotensive individuals and 3.4 micrograms/ml in hypertensive patients.
The prevalence of albuminuria above 20 micrograms/ml was 4% in normotensive, 10% in hypertensive, and 17% in diabetic individuals.
Significant correlations found with smoking (P < 0.0001), hypertension (P < 0.001), and systolic blood pressure (P < 0.01).

Structured PICO

Population

1,006 individuals attending 5 general practitioner offices, comprising 631 hypertensive patients (371 women, 260 men; including 189 diabetic patients) and 375 normotensive controls (217 women, 158 men).

Outcome

Rate of albumin excretion and prevalence of albuminuria assessed by kinetic nephrelometry in morning urine samplessurrogate

Albuminuria prevalence is moderately higher in hypertensive and diabetic patients compared to normotensive individuals, and is significantly driven by smoking, age, and systolic blood pressure.

Cite This Study

mer et al. (1996) studied this question.

synapsesocial.com/papers/6a71bf20ac440176ef2a526f https://doi.org/10.1097/00004872-199605000-00016

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Implication

Albuminuria prevalence rises modestly with hypertension and diabetes; leaves open whether screening improves outcomes in prospective cohorts.

Albuminuria in normotensive and hypertensive individuals attending offices of general practitioners

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Albuminuria in normotensive and hypertensive individuals attending offices of general practitioners

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Also Consider