Key result
Diabetes mellitus accelerates cardiovascular disease progression through interconnected epigenetic, genetic, and cellular signaling mechanisms involving hyperglycemia, inflammation, and dyslipidemia.
Design
Review
Authors
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Current diabetes care unchanged by mechanisms alone; leaves open targeted therapy trials.
This review summarizes the pathophysiological mechanisms, including epigenetic, genetic, and cell-signaling defects, linking diabetes mellitus to the development of cardiovascular disease.
Rodriguez‐Araujo et al. (2018) conducted a review in Cardiovascular disease in diabetes mellitus. Diabetes mellitus accelerates cardiovascular disease progression through interconnected epigenetic, genetic, and cellular signaling mechanisms involving hyperglycemia, inflammation, and dyslipidemia.
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