Key result
Metagenomic analysis of untreated sewage from four countries revealed sequences related to 29 eukaryotic viral families, including known human pathogens and several novel viral genomes.
Population
Untreated sewage samples from the United States, Nigeria, Thailand, and Nepal
Design
Other
Authors
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Sewage metagenomics may enable population viral surveillance; leaves open clinical translation pending validation studies.
Observational
Yes
Deep sequencing of untreated sewage reveals high viral diversity and can be used to monitor shedding of viral pathogens in large populations.
Ng et al. (2012) conducted an observational in Viral diversity in untreated sewage. Deep sequencing of untreated sewage was evaluated on Viral sequences and novel viral genomes. Metagenomic analysis of untreated sewage from four countries revealed sequences related to 29 eukaryotic viral families, including known human pathogens and several novel viral genomes.
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