Key result
Poor glycemic control in patients with type 2 diabetes mellitus was associated with significantly higher mean platelet volume (10.06 fl vs 7.89 fl, p<0.001) compared to good glycemic control.
Why the study?
Platelet parameters may signal the progression of diabetic complications, prompting the evaluation of platelet indices across levels of glycemic control and their association with microvascular complications.
Are platelet indices (MPV and PDW) associated with glycemic control and microvascular complications in patients with type 2 diabetes mellitus?
Population
100 patients with diabetes mellitus
Comparison
Good glycemic control (HbA1c<7%) vs poor glycemic control (HbA1c>7%)
Authors
Loading...
May flag DM complication risk via MPV/PDW; hypothesis-generating and should not yet change practice.
Cross-Sectional (n=100)
No
Are platelet indices (MPV and PDW) associated with glycemic control and microvascular complications in patients with type 2 diabetes mellitus?
Mean Difference: 2.17
Absolute Event Rate: 10.06% vs 7.89%
p-value: p=<0.001
Mean platelet volume and platelet distribution width are significantly elevated in type 2 diabetic patients with poor glycemic control and microvascular complications, suggesting their potential utility as simple predictive biomarkers.
Sangapur et al. (2023) conducted a cross-sectional in Type 2 diabetes mellitus (n=100). Poor glycemic control (HbA1c > 7%) vs. Good glycemic control (HbA1c < 7%) was evaluated on Mean Platelet Volume (MPV) (MD 2.17, p=<0.001). Poor glycemic control in patients with type 2 diabetes mellitus was associated with significantly higher mean platelet volume (10.06 fl vs 7.89 fl, p<0.001) compared to good glycemic control.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: