Key result
Direct physical interactions between ion channels and active transporters form macromolecular complexes termed 'chansporters', representing a newly emerging signaling modality.
Design
Review
Authors
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Chansporter discovery may inform arrhythmia mechanisms; leaves open therapeutic relevance pending functional validation.
This review introduces the concept of 'chansporters'—macromolecular complexes of ion channels and transporters—suggesting a newly emerging signaling modality with potential pathophysiological implications.
Neverisky et al. (2016) reported a review. Chansporters (ion channel-transporter complexes) was evaluated. Direct physical interactions between ion channels and active transporters form macromolecular complexes termed 'chansporters', representing a newly emerging signaling modality.
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