January 23, 2009Pacing and Clinical Electrophysiology
Does ICD Indication Affect Quality of Life and Levels of Distress?
Key result
Primary prophylaxis ICD indication was not associated with poorer quality of life or greater distress compared to secondary prophylaxis across five identified studies.
Why the study?
Does ICD implantation for primary prophylaxis improve or worsen quality of life and distress compared to secondary prophylaxis in patients receiving an ICD?
Population
Patients receiving an implantable cardioverter defibrillator, based on a review of 5 studies with sample…
Comparison
ICD implantation for primary prophylaxis vs ICD implantation for secondary prophylaxis
Design
Systematic_review
Follow-up
2-12 months
Authors
Discussion
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Member takes
Implication
Reassures on equivalent QoL and distress for primary prophylaxis ICDs; confirms comparable patient-reported outcomes versus secondary in systematic data.
Study Design
Type
Systematic Review
Structured PICO
Does ICD implantation for primary prophylaxis improve or worsen quality of life and distress compared to secondary prophylaxis in patients receiving an ICD?
P
Population
Five studies (seven articles) with sample sizes varying from 91 to 426 patients and follow-up ranging from 2 to 12 months, evaluating the impact of ICD indication on patient-centered outcomes.
E
Exposure
ICD implantation for primary prophylaxis
C
Comparator
ICD implantation for secondary prophylaxis
O
Outcome
Patient-centered outcomes including anxiety, depression, disease-specific quality of life, or general quality of life (QoL)patient reported
This review suggests that primary prophylaxis ICD implantation does not adversely impact patient-centered outcomes compared to secondary prophylaxis, which may reassure patients during shared decision-making.
Cite This Study
Pedersen et al. (2009) conducted a systematic review in Life-threatening arrhythmias requiring ICD. Primary prophylaxis ICD indication vs. Secondary prophylaxis ICD indication was evaluated on Patient-centered outcomes (anxiety, depression, disease-specific, or general QoL). Primary prophylaxis ICD indication was not associated with poorer quality of life or greater distress compared to secondary prophylaxis across five identified studies.