Key result
A 78-year-old female with undifferentiated pleomorphic cardiac sarcoma died due to acute cardiac tamponade despite pericardiocentesis.
Why the study?
Primary cardiac sarcoma has a poor prognosis due to late presentation, multiple metastases, and complications, which challenge treatment options.
Case Report (n=1)
Undifferentiated pleomorphic cardiac sarcoma is a rare, highly malignant tumor that can present late with severe complications like cardiac tamponade, leading to a poor prognosis.
Fatal tamponade despite pericardiocentesis in cardiac sarcoma; leaves open optimal management strategies for this rare entity.
Primary cardiac sarcoma is known to have a poor prognosis due to late presentation, multiple metastases, and complications, challenging treatment options. We present a case of a 78-year-old female patient who was admitted to our hospital with progressive dyspnea and chest pain. Echocardiography revealed multiple masses of different shape and size in the left atrium, the left and right ventricles. Cardiac magnetic resonance confirmed multiple cardiac masses with signs of invasion in the myocardium and heterogeneous late gadolinium enhancement in all these masses. A biopsy of the abdominal mass revealed an undifferentiated pleomorphic sarcoma. We planned chemotherapy and supportive measures. Before the initiation of the chemotherapy, the clinical situation worsened dramatically. Despite the pericardiocentesis, the patient died due to cardiac tamponade. An autopsy revealed a massive tumor in the interatrial septum and multiple metastases in both ventricles, lungs, and abdomen.
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Yakovlev et al. (2021) conducted a case report in Undifferentiated pleomorphic cardiac sarcoma (n=1). Pericardiocentesis was evaluated. A 78-year-old female with undifferentiated pleomorphic cardiac sarcoma died due to acute cardiac tamponade despite pericardiocentesis.
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