Key result
Concomitant arterial hypertension in patients with bronchial asthma significantly increased arterial rigidity, manifested by a higher median aortic pulse wave velocity (10.2 m/s vs 7.4 m/s) compared to normotensive asthma patients.
Why the study?
The study aimed to evaluate arterial rigidity parameters in patients with bronchial asthma according to concomitant arterial hypertension during standard anti-inflammatory therapy to facilitate early diagnosis of cardiovascular complications.
Does the presence of concomitant arterial hypertension increase arterial rigidity in patients with bronchial asthma?
Cross-Sectional (n=320)
No
Does the presence of concomitant arterial hypertension increase arterial rigidity in patients with bronchial asthma?
Answers are grounded in this paper and cite their sources.
May support stiffness monitoring in comorbid asthma-hypertension; leaves open whether BP control alters outcomes.
The article deals with changes in arterial rigidity in patients with bronchial asthma, depending on the presence of concomitant hypertension. The aim was to study the arterial rigidity parameters in patients with bronchial asthma depending on the presence of arterial hypertension on the standard antiinflammatory therapy for early diagnosis of complications of the cardiovascular system. A significant increase of arterial rigidity was shown, manifested by an increase in the pulse wave velocity in the aorta (AoPWV) and augmentation index (Alx) in patients with bronchial asthma of moderate and severe course in comparison with the control. In the study of the main indicators of arterial rigidity, depending on the presence or absence of hypertension, it was shown that in the group of patients with hypertension, changes in AoPWV and IA were more significant than in the group of patients with normal blood pressure. Increasing of BMI contributes to the development of arterial rigidity in patients with bronchial asthma. The formation of arterial rigidity is associated with clinical and functional parameters and hypoxemia
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Собко et al. (2019) conducted a cross-sectional in Bronchial asthma and arterial hypertension (n=320). Arterial hypertension vs. Normal blood pressure was evaluated on Aortic pulse wave velocity (AoPWV) (p=<0.001). Concomitant arterial hypertension in patients with bronchial asthma significantly increased arterial rigidity, manifested by a higher median aortic pulse wave velocity (10.2 m/s vs 7.4 m/s) compared to normotensive asthma patients.
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