Key result
Asthma is linked to a ~3.7-fold higher prevalence of arterial hypertension compared to controls.
Why the study?
The relationship between asthma and arterial hypertension, which frequently co-exist, has unclear aspects that require further evaluation.
Is asthma associated with an increased prevalence of arterial hypertension?
Case-Control (n=80)
No
Is asthma associated with an increased prevalence of arterial hypertension?
Asthma is independently associated with a significantly higher prevalence of arterial hypertension, highlighting the utility of ambulatory blood pressure monitoring in this population to detect unrecognized hypertension.
Answers are grounded in this paper and cite their sources.
Asthma independently associated with higher hypertension prevalence; leaves open need for targeted screening or causal confirmation in prospective studies.
Background: several studies report an increased risk for asthmatic subjects to develop arterial hypertension and the relationship between these two diseases, frequently co-existing, still has some unclear aspects. Methods: The BADA (blood pressure levels, clinical features and markers of subclinical cardiovascular damage of asthma patients) study is aimed to evaluate the prevalence of the cardiovascular comorbidities of asthma and their impact on the clinical outcome. The main exclusion criteria were the presence of other respiratory diseases, current smoking, any contraindication to ambulatory blood pressure monitoring (ABPM). Results: The overall percentage of asthmatics having also hypertension was 75% (30 patients) vs. 45% (18 patients) of the control group (p: 0.012). Reduced level of FEV1 (but not inhaled steroid therapy) was associated to newly-diagnosed hypertension (p: 0.0002), higher day SBP levels (p: 0.003), higher day DBP levels (p: 0.03), higher 24 h-SBP levels (p: 0.005) and higher 24h-DBP levels (p: 0.03). The regression analysis performed taking into account sex, age, diabetes, fasting glucose, and body mass index confirms the independent role played by asthma: odds ratio (OR): 3.66 (CI: 1.29–11.1). Conclusions: hypertension is highly prevalent in asthma; the use of ABPM has allowed the detection of a considerable number of unrecognized hypertensives.
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Raimondo et al. (2020) conducted a case-control in Asthma (n=80). Asthma vs. Controls without respiratory disease was evaluated on Prevalence of arterial hypertension (OR 3.66, 95% CI 1.29-11.1, p=0.008). Asthma was independently associated with a higher prevalence of arterial hypertension compared to controls without respiratory disease.
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